I am new to this site so I apologize if i am not great at explaining. My family has a 2008 Toyota Sienna that we replaced the radiator and thermostat on and we're still having problems. We think this unhooked plug (See below) but cannot figure out where it goes. If you need me to add more photos I can.
My Sienna is an 06 and I too have that connector showing and not connected to anything. What problems are you having with your Sienna? Maybe a member with your 2GR-FE engine can chime in to help.